In the mid-1940s, Bombay Talkies advertised in the newspaper for a new face to star in their upcoming project. Meera Mishra, who was originally from Kanpur and a popular socialite amongst the elites, was the one chosen from the lot. As she was well versed in both Bengali and Hindi, she was chosen to star in Nitin Bose’s bilingual venture Nouka Dubi (1946)/ Milan (1947). In Nouka Dubi, she starred opposite Abhi Bhattacharya. Milan starred Meera opposite then-newcomer Dilip Kumar alongside Ranjana and Pahadi Sanyal, who appeared in both versions as well.
An unlikely choice for a woman married to an IPS officer to join the film industry, Meera Mishra raised a lot of interest when she made her debut. Initially, she intended to quit the cinema industry after these two films but due to the untimely death of her husband, Kripa Sindhu Mishra, during the Delhi riots after partition, she continued with her career. The couple had a son called Jishnu together.
She appeared in Bengali films like Abarta (1949), Eki Gramer Chele (1950), and Sandhyabelar Rupkatha (1950). The other Bengali-Hindi bilingual film she starred in was Agradoot’s Pather Dabi/Sabyasachi (1948) which was based on a story by Sarat Chandra Chatterjee. She also acted in Hindi films such as Ghar Ki Numaish (1949), nationalistic films such as Kashmir Hamara Hai (1950), and Azadi Ke Baad (1951). She was lauded for her performance in Chhoti Maa (1952). A Filmfare review commented on her skillful portrayal of the tragic character of Bindu in the film.
In 1953, she tied the knot with Mr Ranjit Gupta who was the Chief Secretary to the Government of West Bengal. She finally quit the film world to focus on her family. Meera Mishra passed away in Calcutta in 2008.